Health technology assessment of targeted therapies

The aim is to describe the specifics of health technology assessment (HTA) of targeted therapies and discuss important issues related to current research methods and application of HTA process in Bulgaria. Analytic study based on literature review and content analysis of HTA guidelines and Bulgarian HTA legislation wеre performed. Specifics of HTA of targeted therapies were analyzed through determining the characteristics of the object and the subject of analysis. Characteristics and types of targeted therapies were defined. Specific features and challenges of HTA of targeted therapies were discussed. The issue of companion diagnostic tests associated with targeted therapies was highlighted.  There are important methodological issues of HTA of targeted therapies determined by the object of analysis that should be taken into consideration both in the process of assessment and appraisal of targeted therapies in Bulgaria. For more information click here.