Neuroprotective mechanisms of coenzyme Q10

PubMed, the Internet portal of biomedical and life sciences literature, indexed an interesting article about the clinical aspects of coenzyme Q10 (Curr Opin Clin Nutr Metab Care. 2005 Nov;8(6):641-6). Authors are Littarru GP and Tiano L from the Institute of Biochemistry, Polytechnic University of Marche, Via Ranieri, Ancona, Italy. Work on different neurological diseases, involving mitochondrial dysfunction and oxidative stress, highlights some of the neuroprotective mechanisms of coenzyme Q10. A 4-year follow-up on 10 Friedreich’s Ataxia patients treated with coenzyme Q10 and vitamin E showed a substantial improvement in cardiac and skeletal muscle bioenergetics and heart function. The latest findings highlight the beneficial role of coenzyme Q10 as coadjuvant in the treatment of syndromes, characterized by impaired mitochondrial bioenergetics and increased oxidative stress. To access the full abstract of the article, click here.