Barraquer-Simons syndrome

A new disease profile is added to our database – Barraquer-Simons syndrome. Acquired partial lipodystrophy, also known as Barraquer-Simons syndrome or cephalothoracic lipodystrophy, is one of the rare forms of lipodystrophy. Acquired partial lipodystrophy usually begins in childhood, at a median age of 8 years. It predominantly affects females (ratio 4:1) and often follows an acute febrile illness. Fat loss is usually limited to the face, trunk, and upper extremities. Simultaneously, fat hypertrophy occurs in the lower extremities. This is a rare syndrome with unknown prevalence, although it is more common than the generalized form of acquired lipodystrophy (Lawrence syndrome). To receive a full description of this rare disease absolutely free of charge, please click here and send us a request. The profile was written by our consultant in genetics – Dr. Dimitrina Konstantinova, PhD.