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The National Centre for Rare Diseases within the Italian National Health Institute is organizing next week a workshop on the clinical practice guidelines for rare diseases. The event will take place on 23-24 Febryary 2012 in Rome. The very first event on this issue is aiming at sharing experiences and knowledge and discussing critical methodological problems, linked to the specificity of rare diseases. The workshop is free of charge and open to all interested stakeholders. For further information and to register, please visit organizers’ website.