Histiocytosis

A new disease profile is added to our database – Histiocytosis. Histiocytosis is a generic name for a group of syndromes characterized by an abnormal increase in the number of certain immune cells called histiocyte cells. These include monocytes, macrophages, and dendritic cells. There are 3 major classes of histiocytoses. The Langerhans cell histiocytosis is also called histiocytosis X. Langerhans cell histiocytosis is a rare disorder that occurs when there are too many of a type of white blood cell called a Langerhans cell (named for a German scientist). The other 2 classes are non-Langerhans cell histiocytosis (also known as hemophagocytic syndrome) and malignant histiocytosis syndrome (now known as T-cell lymphoma). No occupational causes or geographic predispositions are recognized. The cause of Langerhans cell histocytosis (LCH) is not entirely understood. Researchers are studying viral infections or environmental factors that could lead to this disorder. To receive a full description of this rare disease absolutely free of charge, please click here and send us a request. The profile was written by our consultant in immunology – Prof. Dr. Mariana Murdjeva, MD, PhD.