Crystal storing histiocytosis

PubMed, the Internet portal of biomedical and life sciences literature, indexed an interesting article, entitled “Crystal storing histiocytosis of the skin associated with multiple myeloma.” (Int J Dermatol. 2006 Dec;45(12):1408-11). Authors are Pock L, Stuchlik D and Hercogova J, from the Dermatopathological Laboratory, Department of Dermatology, District Hospital Pardubice, Prague, Czech Republic. Crystal storing histiocytosis (CSH) imitating rhabdomyom is a very rare disease entity involving different tissues. The skin is involved in extremely rare cases. A 62-year-old woman presented with a large red infiltrated verrucosus lesion on the anterior aspect of the chest and on the neck. The skin biopsy revealed histiocytes throughout the whole dermis containing thin crystaloid structures in the cytoplasm. Upon histopathological examination, crystal-storing histiocytosis was diagnosed and consequently a hematological examination revealed multiple myeloma IgG Kappa. To access the full abstract of the article, click here.