Primary central nervous system lymphoma

PubMed, the Internet portal of biomedical and life sciences literature, indexed an interesting article, entitled “High-dose methotrexate and primary central nervous system lymphoma.” (J Neurosci Nurs. 2007 Apr;39(2):83-8). Authors are Fahey JB and DiMaggio C, from the Massachusetts General Hospital, Boston, MA, USA. Primary central nervous system lymphoma (PCNSL) is a rare disease that is managed differently from other primary brain tumors and other types of systemic lymphomas. The use of high-dose methotrexate (HD-MTX) has improved survival rates. This article describes the experience of a patient treated with HD-MTX and outlines the essential aspects of care for the bedside practitioner. To access the full abstract of the article, click here.