Multifocal calcifying epithelial odontogenic tumor

PubMed, the Internet portal of biomedical and life sciences literature, indexed an interesting article, entitled “Multifocal calcifying epithelial odontogenic tumor.” (Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Aug;104(2):e30-4). Authors are Sedghizadeh PP, Wong D, Shuler CF, et al., from the Division of Diagnostic Sciences, Center for Craniofacial Molecular Biology, School of Dentistry, University of Southern California, Los Angeles, USA. The calcifying epithelial odontogenic tumor (CEOT), or Pindborg tumor, is a rare and benign odontogenic neoplasm that affects the jaw. The most common manifestation of CEOT is a unifocal or localized lesion of the involved jaw, which may appear clinically as a hard tissue swelling and radiographically as a mixed radiolucent-radiopaque mass. In this article, the authors present a unique case of CEOT affecting multiple sites in the maxilla and mandible of a 51-year-old white man. Though biopsy samples from all involved sites revealed similar histopathologic features consistent with CEOT, the fact that there was a multifocal presentation is an unusual phenomenon for CEOT and has never been reported. To access the full abstract of the article, click here.