Motor unit number estimation in amyotrophic lateral sclerosis

PubMed, the Internet portal of biomedical and life sciences literature, indexed an interesting article, entitled Motor unit number estimation (mune) as a quantitative measure of disease progression and motor unit reorganization in amyotrophic lateral sclerosis (Int J Neurosci. 2007 Sep;117(9):1229-36). Authors are Sartucci F Maritato P Moscato G et al. from the Department of Neuroscience, Clinical Neurophysiology, Pisa University Medical School, Pisa, Italy. Motor Unit Number Estimation (MUNE), a technique allowing to estimate the number of functioning Motor Units (MU) in single muscles, was used to score the disease’s severity and progression rate in a group of 58 patients with Amyotrophic Lateral Sclerosis (ALS). The results confirm that MUNE is a suitable tool to quantify the pathological changes in MU in patients with ALS. To access the full abstract of the article, click here.