Treatment of Cerebral Venous and Sinus Thrombosis

PubMed, the Internet portal of biomedical and life sciences literature, indexed an interesting article, entitled Treatment of Cerebral Venous and Sinus Thrombosis (Front Neurol Neurosci. 2008;23:132-143.). Authors are Masuhr F Einhäupl K. et al., from the Department of Neurology, Charité – Universitätsmedizin Berlin, Berlin, Germany. Cerebral venous and sinus thrombosis (CVST) is a rather rare disease which accounts for less than 1% of all strokes. Current therapeutic measures which are used in clinical practice include the use of anticoagulants such as dose-adjusted intravenous heparin or body weight-adjusted subcutaneous low molecular weight heparin, the use of thrombolysis, and symptomatic therapy including control of seizures and elevated intracranial pressure.There are no controlled data about the risks and benefits of certain therapeutic measures to reduce an elevated intracranial pressure (with brain displacement) in patients with severe CVST. Antiedema treatment (including hyperventilation, osmotic diuretics, craniectomy) should be used as life-saving interventions. To access the full abstract of the article, click here.