Recessive dystrophic epidermolysis bullosa is a devastating genodermatosis characterized by generalized skin fragility, severe blistering, and wounding that heals with mutilating scarring. Patients are in constant need of effective wound therapies and in continuous risk of infections and anaemia, which can lead to early death.
University of California researchers have tried a fractionated CO2 laser therapy on a 22-year-old man with RDEB. His 9-month-old, 7 cm in diameter non-healing wound completely re-epithelized after 2 laser procedures 4 weeks apart of each other. This novel intervention of using fractionated CO2 for photo-microdebridement has the potential to accelerate healing and decrease patient mortality.
A paediatric testing of the therapy is pending which can add another therapeutic approach to wound management.
You can read the whole publication here.