Pathogenic insights from Huntington’s disease-like 2 and other Huntington’s disease genocopies

The journal Current Opinion in Neurology has published an article about the Huntington’s disease. Huntington’s disease-like 2 (HDL2) is a rare, progressive, autosomal dominant neurodegenerative disorder that genetically, clinically, and pathologically closely resembles Huntington’s disease. Studies examining in parallel the genetic, clinical, neuropathological, and mechanistic similarities between Huntington’s disease and HDL2 have begun to identify points of convergence between the pathogenic pathways of the two diseases. The full-text article you can find here.