HAE review paper

PubMed, the Internet portal of biomedical and life sciences literature, indexed an interesting article, entitled “Hereditary angioedema“ (Curr Opin Hematol. 2005 Nov;12(6):493-8). Author of the article is Bracho FA from Lombardi Cancer Center, Georgetown University Hospital, Washington, USA. Hereditary angioedema is an autosomal-dominant deficiency of C1 inhibitor and is often misdiagnosed and poorly treated. Diagnosis requires careful medical and family history and the measurement of functional C1 inhibitor and C4 levels. New agents such as recombinant C1 inhibitor, kallikrein inhibitors, and bradykinin inhibitors may offer safer and more tolerable treatments. On a recent workshop clinicians have produced consensus documents and expert reviews. The pharmaceutical industry has initiated clinical trails with novel agents. To access the full abstract of the text study, click here.