Leiomyomatosis peritonealis disseminata

PubMed, the Internet portal of biomedical and life sciences literature, indexed an interesting article, entitled “Familial clustering of Leiomyomatosis peritonealis disseminata: an unknown genetic syndrome?“ (BMC Gastroenterol. 2005 Oct 13;5(1):33). Authors are Halama N, Grauling-Halama SA and Daboul I. Leiomyomatosis peritonealis disseminata (LPD) is defined as the occurrence of multiple tumorous intraabdominal lesions. LPD is a rare disease with only about 100 cases reported. The usual course of LPD is benign with the majority of the patients being premenopausal females. Only two cases involving men have been reported, no syndrome or familial occurrence of LPD has been described. The authors describe a Caucasian-American family in which six members (three men) are diagnosed with Leiomyomatosis peritonealis disseminata (LPD). Furthermore, they describe the association of LPD with Raynaud’s syndrome and Prurigo nodularis. To access the full abstract of the article, click here.