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PubMed, the Internet portal of biomedical and life sciences literature, indexed an interesting article, entitled Thrombotic thrombocytopenic purpura and bone marrow necrosis as the initial presentation of lung cancer (Clin Appl Thromb Hemost. 2007 Oct;13(4):449-52). Authors are Sevinc A Kalender ME Pehlivan Y et al., from the Department of Medical Oncology, Gaziantep University, School of Medicine, Gaziantep Oncology Hospital, Gaziantep, Turkey. Thrombotic thrombocytopenic purpura (TTP) is a disseminated form of thrombotic microangiopathy. Although most cases are held to be idiopathic, its association with malignancy is well recognized, and it usually occurs at the terminal stage of cancer. Bone marrow necrosis (BMN) is another rare disorder defined pathologically as the necrosis of myeloid tissue and medullary stroma with preservation of bone. Although hematologic malignancy is the most common underlying disease associated with BMN, it can also be caused by solid tumors. The occurrence of TTP with BMN associated with lung cancer has not been reported in the English literature. To access the full abstract of the article, click here.

PubMed, the Internet portal of biomedical and life sciences literature, indexed an interesting article, entitled Laparoscopic Internal Marsupializaton for Large Nonparasitic Splenic Cysts: Effective Organ-Preserving Technique. (World J Surg. 2007 Nov 9). Authors are Palanivelu C Rangarajan M Madankumar MV et al., from the Division of Surgical Gastroenterology, Department of Surgery, GEM Hospital, India. Primary splenic cyst is a rare disease, and therefore there is no information regarding its optimal management. Most such cysts are classified as epithelial cysts. During the last few years, the laparoscopic approach has gained increasing acceptance in splenic surgery. We present our experience with the laparoscopic (organ-preserving) management of splenic cysts. Laparoscopic partial cystectomy/marsupialization is an acceptable procedure for the treatment of splenic cysts; and after short to mid-term follow-up, it seems that a reasonable rate of success is possible. To access the full abstract of the article, click here.

PubMed, the Internet portal of biomedical and life sciences literature, indexed an interesting article, entitled Hypocalcemic seizure due to congenital rickets in the first day of life. ( Turk J Pediatr. 2007 Jul-Sep;49(3):301-3.). Authors are Erdeve O Atasay B Arsan S et al., from the Division of Neonatology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey. Congenital rickets is considered a rare disease entity in the newborn period. Hypocalcemic seizure due to congenital rickets has been reported, but this symptom generally appears at the earliest at the end of the first month of life. A congenital rickets case presented unusually with seizure on the first day of life. Despite improved prenatal care offered today, congenital rickets still occurs. It seems that vitamin D deficiency in the neonate secondary to maternal deficiency should be a consideration for the pediatrician or neonatologist caring for newborns. Physicians should be aware of risk factors that can trigger the development of this condition. To access the full abstract of the article, click here.